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In addition, transcriptomic analysis of brains of 2 independent SCA3 transgenic mouse models reported downregulation of genes involved in glutamatergic and alpha-adrenergic neurotransmission and alterations in CREB pathways, as well as in axon guidance molecules, some of these alterations being already present at presymptomatic ages [117, 122]
TAMBEN TE PUEDE INTERESAR: DESCUBRE EL PODER DE LOS PPTIDOS "TIRZEPATIDE" EL PPTIDO REVOLUCIONADOR RETATRUTIDE EL PPTIDO DE LTIMA GENERACIN
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